Super Methyl-SP supports methylation reactions, important for metabolism of homocysteine, by providing a combination of targeted nutrients and cofactors, such as trimethylglycine at 550 mg and MSM at 50 mg per serving.* This formula includes the antioxidant vitamins C and E, as well as high-potency riboflavin, vitamin B6, folate, and vitamin B12. In addition, this formula includes a biologically active form of folate (5-methyltetrahydrofolic acid or 5-MTHF), which is normally produced and available to the body only at the final stage of the folate metabolic process*. Also available, Methyl SPTM (K14) with 1200 mcg of folate per serving.